Educational Background

  • B.Sc., Xiamen University
  • M.Sc., Beijing Normal University
  • Ph.D., Institute of Chemistry, Chinese Academy of Sciences
  • Postdoctoral: Sanford Burnham Prebys Medical Discovery Institute, University of Texas Health Science Center at San Antonio

Current Research Interests

  • Fundamental and methodological studies of mass spectrometry imaging; ambient ionization; trace lipidomic analysis.

Selected Publications

  1. Wang C., Wang J., Qin C, Han X. Analysis of monohexosyl alkyl (alkenyl)-acyl glycerol in brain samples by shotgun lipidomics, Anal Chim Acta 2020, 1129: 143-149.
  2. Wang, J., Han, X. Analytical challenges of shotgun lipidomics at different resolution of measurements, TrAC-Trend Anal Chem 2019, 121,115697,
  3. Wang, J., Wang, C. & Han, X. Tutorial on lipidomics, Anal Chim Acta 2019, 1061, 28-41, doi:10.1016/j.aca.2019.01.043.
  4. Wang, J., Wang, C. & Han, X. Enhanced coverage of lipid analysis and imaging by matrix-assisted laser desorption/ionization mass spectrometry via a strategy with an optimized mixture of matrices, Anal Chim Acta, 2018, 1000, 155-162, doi:10.1016/j.aca.2017.09.046.
  5. Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S., Wang J., Stohlmann, K., Brandslund, I., Christensen, C., Jorgensen, M. E., Linneberg, A., Pedersen, O., Kiebish, M. A., Qvortrup, K., Han, X., Pedersen, B. K., Jastroch, M., Mandrup, S., Kjaer, A., Gygi, S. P., Hansen, T., Gillum, M. P., Grarup, N., Emanuelli, B., Nielsen, S., Scheele, C., Tseng, Y. H., Faergeman, N. J. & Gerhart-Hines, Z. Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis, Cell Metab 2018, 28, 159-174 e111, doi:10.1016/j.cmet.2018.05.003.
  6. Wang J., Sun, J., Wang, J., Liu, H., Xue, J. & Nie, Z. Hexagonal boron nitride nanosheets as a multifunctional background-free matrix to detect small molecules and complicated samples by MALDI mass spectrometry, Chem Commun, 2017, 53, 8114-8117, doi:10.1039/c7cc02957h (Cover Story).
  7. Wang J., Qiu, S., Chen, S., Xiong, C., Liu, H., Wang, J., Zhang, N., Hou, J., He, Q. & Nie, Z. MALDI-TOF MS imaging of metabolites with a N-(1-naphthyl) ethylenediamine dihydrochloride matrix and its application to colorectal cancer liver metastasis, Anal Chem 2015, 87, 422-430, doi:10.1021/ac504294s.
  8. He, Q., Badu-Tawiah, A. K., Chen, S., Xiong, C., Liu, H., Zhou, Y., Hou, J., Zhang, N., Li, Y., Xie, X., Wang J., Mao, L. & Nie, Z. In situ bioconjugation and ambient surface modification using reactive charged droplets, Anal Chem 2015, 87, 3144-3148, doi:10.1021/ac504111f.
  9. Liu, H., Chen, R., Wang, J., Chen, S., Xiong, C., Wang J., Hou, J., He, Q., Zhang, N., Nie, Z. & Mao, L. 1,5-Diaminonaphthalene hydrochloride assisted laser desorption/ionization mass spectrometry imaging of small molecules in tissues following focal cerebral ischemia, Anal Chem 2014, 86, 10114-10121, doi:10.1021/ac5034566.
  10. Xiong, C., Zhou, X., Wang J., Zhang, N., Peng, W. P., Chang, H. C. & Nie, Z. Ambient aerodynamic desorption/ionization method for microparticle mass measurement, Anal Chem 2013, 85, 4370-4375, doi:10.1021/ac303565a.
  11. Chen, S., Zheng, H., Wang J., Hou, J., He, Q., Liu, H., Xiong, C., Kong, X. & Nie, Z. Carbon nanodots as a matrix for the analysis of low-molecular-weight molecules in both positive- and negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and quantification of glucose and uric acid in real samples, Anal Chem 2013, 85, 6646-6652, doi:10.1021/ac401601r.
  12. Chen, S., Chen, L., Wang J., Hou, J., He, Q., Liu, J., Wang, J., Xiong, S., Yang, G. & Nie, Z. 2,3,4,5-Tetrakis(3',4'-dihydroxylphenyl)thiophene: a new matrix for the selective analysis of low molecular weight amines and direct determination of creatinine in urine by MALDI-TOF MS, Anal Chem 2012, 84, 10291-10297, doi:10.1021/ac3021278.