Educational Background

  • B.Sc. (Hons.), The Chinese University of Hong Kong
  • Ph.D., Houston, USA

Current Research Interests

  • Biomolecular modeling and QSPR.

Selected Publications

  1. M. Guo, G. Guo, J. Xiao, X. Sheng, X. Zhang, Y. Tie, Y.-K. Cheng, X. Ji, “Ginsenoside Rg3 Stereoisomers Differentially Inhibit Vascular Smooth Muscle Cell Proliferation and Migration in Diabetic Atherosclerosis”, J. Cell. Mol. Med. 22, 3202-3214 (2018).
  2. P. Zhao, S.-K. Chen, Y.-H. Cai, X. Lu, Z. Li, Y.-K. Cheng, C. Zhang, X. Hu, X. He, H.-B. Luo, “The Molecular Basis for the Inhibition of PDE-4D by Three Natural Resveratrol Analogs”, Biochim. Biophys. Acta., 1834, 2089-2096 (2013).
  3. Z. Li, Y.-H. Cai, Y.-K. Cheng, X. Lu, Y.-X. Shao, X. Li, M. Liu, P. Liu, H.-B. Luo, “Identification of Novel PDE-4D Inhibitors Prescreened by MD-augmented Modeling and Validated by Bioassay”, J. Chem. Info. Model., 53, 972-981 (2013).
  4. J. K. C. Lau, X. B. Li and Y. K. Cheng, “A Substrate Selectivity and Inhibitor Design Lesson from the PDE10-cAMP Crystal Structure”, J. Phys. Chem. B, 114, 5154-5160 (2010).
  5. H. B. Luo, C. Zheng and Y. K. Cheng, “Is Phosphatidylcholine-Saturated Alkyl Column a Convenient Replacement for Immobilized-Artificial-Membrane?”, J. Chromatgr. A, 1176, 100-106 (2007).
  6. Y. K. Cheng and P. J. Rossky, “Surface Topography Dependence of Biomolecular Hydrophobic Hydration”, Nature, 392, 696-699 (1998).