Educational Background

  • B.Sc. (Hons.), The Chinese University of Hong Kong
  • Ph.D., Houston, USA

Current Research Interests

  • Biomolecular modeling and QSPR.

Selected Publications

  1. X. Liang, W. Ye, W. Thor, L. Sun, B. Wang, S. He, Y.-K. Cheng, and C.S. Lee, “Construction of Cyclopenta[b]pyran-2-ones via Chemoselective (3+2) Cycloaddition between 2-Pyrones and Vinyl Cyclopropanes”, Org. Chem. Front. 7, 840-845 (2020).
  2. X. Huang, W. Thor, X. Feng, L. Kang, M. Yang, C.-S. Lee, Y.-K. Cheng, and S. He, “(4+3) cycloadditions of allenyl ether-derived oxygen-stabilized oxyallyls with furans”, Org. Chem. Front. 7, 255-260 (2020).
  3. J. Cao, W. Thor, S. Yang, M. Zhang, W. Bao, L. Zhu, W. Yang, Y.-K. Cheng, and C.-S. Lee, “Synthesis of the Tricyclic Picrotoxane Motif by an Oxidative Cascade Cyclization”, Org. Lett. 21, 4896-4899 (2019).
  4. M. Guo, G. Guo, J. Xiao, X. Sheng, X. Zhang, Y. Tie, Y.-K. Cheng, X. Ji, “Ginsenoside Rg3 Stereoisomers Differentially Inhibit Vascular Smooth Muscle Cell Proliferation and Migration in Diabetic Atherosclerosis”, J. Cell. Mol. Med. 22, 3202-3214 (2018).
  5. J. K. C. Lau, X. B. Li and Y. K. Cheng, “A Substrate Selectivity and Inhibitor Design Lesson from the PDE10-cAMP Crystal Structure”, J. Phys. Chem. B, 114, 5154-5160 (2010).
  6. H. B. Luo, C. Zheng and Y. K. Cheng, “Is Phosphatidylcholine-Saturated Alkyl Column a Convenient Replacement for Immobilized-Artificial-Membrane?”, J. Chromatgr. A, 1176, 100-106 (2007).
  7. Y. K. Cheng and P. J. Rossky, “Surface Topography Dependence of Biomolecular Hydrophobic Hydration”, Nature, 392, 696-699 (1998).