Educational Background

  • B.Sc., Peking University
  • M.Sc., Peking University
  • Ph.D., Hong Kong Baptist University
  • Postdoctoral: Hong Kong University of Science and Technology

Current Research Interests

  • Quantitative biology, regulation of signaling and metabolic pathways, high-throughput “-omics” studies, big data analysis, systems biology and computational modeling.

Selected Publications

  1. Yang, Z., Guo, G., Yang, N., Pun, S.S., Ho, T.K.L., Ji, L., Hu, I., Zhang, J., Burlingame, A.L., and Li, N. The change of gravity vector induces short-term phosphoproteomic alterations in Arabidopsis. Journal of proteomics, 103720 (2020).
  2. Shao, X., Zhang, H., Yang, Z., Zhong, H., Xia, Y., and Cai, Z. NAD tagSeq for transcriptome-wide identification and characterization of NAD(+)-capped RNAs. Nature protocols 15, 2813-2836 (2020).
  3. Shao, X., Zhang, H., Yang, Z., Zhu, L., and Cai, Z. Quantitative Profiling of Protein-Derived Electrophilic Cofactors in Bacterial Cells with a Hydrazine-Derived Probe. Analytical chemistry 92, 4484-4490 (2020).
  4. Song, Y., Qi, Z., Zhang, Y., Wei, J., Liao, X., Li, R., Dong, C., Zhu, L., Yang, Z., and Cai, Z. Effects of exposure to ambient fine particulate matter on the heart of diet-induced obesity mouse model. Sci Total Environ 732, 139304 (2020).
  5. Wang, K., Yang, Z., Qing, D., Ren, F., Liu, S., Zheng, Q., Liu, J., Zhang, W., Dai, C., Wu, M., Chehab, E.W., Braam, J., and Li, N. Quantitative and functional posttranslational modification proteomics reveals that TREPH1 plays a role in plant touch-delayed bolting. Proceedings of the National Academy of Sciences of the United States of America 115, E10265-E10274 (2018).
  6. Liu, S., Yu, F., Yang, Z., Wang, T., Xiong, H., Chang, C., Yu, W., and Li, N. Establishment of Dimethyl Labeling-based Quantitative Acetylproteomics in Arabidopsis. Molecular & cellular proteomics : MCP 17, 1010-1027 (2018).
  7. Qing, D., Yang, Z., Li, M., Wong, W.S., Guo, G., Liu, S., Guo, H., and Li, N. Quantitative and Functional Phosphoproteomic Analysis Reveals that Ethylene Regulates Water Transport via the C-Terminal Phosphorylation of Aquaporin PIP2;1 in Arabidopsis. Molecular plant 9, 158-174 (2016).
  8. Zhu, X., Yu, F., Yang, Z., Liu, S., Dai, C., Lu, X., Liu, C., Yu, W., and Li, N. In planta chemical cross-linking and mass spectrometry analysis of protein structure and interaction in Arabidopsis. Proteomics 16, 1915-1927 (2016).
  9. Yang, Z., and Li, N. Absolute quantitation of protein posttranslational modification isoform. Methods in molecular biology 1306, 105-119 (2015)
  10. Yang, Z., Guo, G., Zhang, M., Liu, C.Y., Hu, Q., Lam, H., Cheng, H., Xue, Y., Li, J., and Li, N. Stable Isotope Metabolic Labeling-based Quantitative Phosphoproteomic Analysis of Arabidopsis Mutants Reveals Ethylene-regulated Time-dependent Phosphoproteins and Putative Substrates of Constitutive Triple Response 1 Kinase. Molecular & cellular proteomics : MCP 12, 3559-3582 (2013).
  11. Lin, S.H., Yang, Z., Shen, Y., and Cai, Z.W. LC/MS-based non-targeted metabolomics for the investigation of general toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J and DBA/2J mice. International Journal of Mass Spectrometry 301, 29-36 (2011).
  12. Lin, S., Yang, Z., Zhang, X., Bian, Z., and Cai, Z. Hippocampal metabolomics reveals 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity associated with ageing in Sprague-Dawley rats. Talanta 85, 1007-1012 (2011).