Educational Background

  • B.Sc. (Hons.), The Chinese University of Hong Kong
  • Ph.D., Iowa State University, USA
  • Postdoctoral: University of Chicago, USA

Current Research Interests

Selected Publications

  1. Y. Li, D. Xu, H. N. Chan, C. Y. Poon, H. W. Li and M. S. Wong, “Dual-Modal NIR-Fluorophore Conjugated Magnetic Nanoparticle for Imaging Amyloid-β Species In Vivo”, Small, doi: 10.1002/smll.201800901 (2018).
  2. Y. Guo, F. Shen, Y. Cheng, Y. Xie, H. Yu, W. Yao, H. W. Li, H. Qian and R Pei, “The light-up fluorescence of AgNCs in a DNA bulb”, Nanoscale, 10, 11517-11523 (2018).
  3. X. Li, L. Wei, L. Pan, Z. Yi, X. Wang, Z. Ye, L. Xiao, H. W. Li, and J. Wang, “Homogeneous Immunosorbent Assay Based on Single-Particle Enumeration Using Upconversion Nanoparticles for the Sensitive Detection of Cancer Biomarkers”, Anal. Chem., 90 (7), 4807-4814 (2018).
  4. D. Zhang, L. Wei, M. Zhong, L. Xiao, H. W. Li and J. Wang, “The morphology and surface charge-dependent cellular uptake efficiency of upconversion nanostructures revealed by single-particle optical microscopy” Chem. Sci., 9 (23), 5260-5269 (2018).
  5. J. Qian, D. Xu, S. L. Ho, K. Wang, M. S. Wong and H. W. Li, “Magnetically controlled immunosensor for highly sensitive detection of carcinoembryonic antigen based on an efficient “turn-on” cyanine fluorophore”, Sens. Actuators B: Chem., 258, 133-140 (2018).
  6. D. He, L. Hai, H. Wang, R. Wu and H. W. Li, “Enzyme-free quantification of exosomal microRNA by the target-triggered assembly of the polymer DNAzyme nanostructure”, Analyst, 143(4), 813-816 (2018).
  7. D. He, L. Hai, X. He, X. Yang and H. W. Li, “Glutathione-Activatable and O /Mn2+-Evolving Nanocomposite for Highly Efficient and Selective Photodynamic and Gene-Silencing Dual Therapy” Adv. Funct. Mater., 27(46), 1704089 (2017).
  8. Y. Li, D. Xu, A. Sun, S. L. Ho, C. Y. Poon, H. N. Chan, Olivia T. W. Ng, K. K. L. Yung, H. Yan, H. W. Li and M. S. Wong, “Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity” Chem. Sci., 8(12), 8279-8284 (2017).
  9. D. G. He, X. He, X. Yang and H. W. Li, “A smart ZnO@polydopamine-nucleic acid nanosystem for ultrasensitive live cell mRNA imaging by the target-triggered intracellular self-assembly of active DNAzyme nanostructures”, Chem. Sci., 8(4), 2832-2840 (2017).
  10. H. N. Chan, D. Xu, S. L. Ho, M. S. Wong and H. W. Li, “Ultra-sensitive detection of protein biomarkers for diagnosis of Alzheimer's disease”, Chem. Sci., 8(5), 4012-4018 (2017).
  11. C. Y. Poon, L. Wei, Y. L. Xu, B. Chen, L. H. Xiao and H. W. Li, “Quantification of Cancer Biomarkers in Serum Using Scattering-Based Quantitative Single Particle Intensity Measurement with a Dark-Field Microscope”, Anal. Chem., 88(17), 8849-8856 (2016).
  12. S. L. Ho, D. Xu, M. S. Wong and H. W. Li, “Direct and multiplex quantification of protein biomarkers in serum samples using an immuno-magnetic platform”, Chem. Sci., 7(4), 2695-2700 (2016).