HKBU joint research develops multifunctional nanoparticle for diagnosis and treatment of glioma

The research team co-led by Dr Wang Yi, Assistant Professor, and Professor Law Ga-lai, Professor of the Department of Applied Biology and Chemical Technology at the Hong Kong Polytechnic University, has synthesized a nanoparticle named TRZD that can perform the dual function of diagnosing and treating glioma in the brain.

TRZD emits persistent luminescence for the diagnostic imaging of glioma tissues in vivo and inhibits the growth of tumor cells by aiding the targeted delivery of chemotherapy drugs. The nanoparticle offers hope for the early diagnosis and treatment of glioma, especially cerebellar glioma, which is even harder to detect and cure with existing methods.

The research results have been published in Science Advances, an international scientific journal.

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