Teaching Staff
 
CHUNG, Arthur, C. K. - Research Assistant Professor
鍾志剛

Educational Background:
  • B.Sc., The Chinese University of Hong Kong
  • M.Ph, The Chinese University of Hong Kong
  • Ph.D., University of Oklahoma, USA
  • Postdoctoral: Baylor College of Medicine, USA

Current Research Interests:

  • Persistent organic pollutants (POP), TGF-β signaling pathway, diabetes, renal diseases, cardiovascular diseases, MALDI imaging.
Contacts:  
Selected Publications:
  1. Y Zhou, AC Chung, HM Lee, G Xu, JCN Chan, APS Kong, “Sirt3 deficiency increased the vulnerability of the pancreatic beta cells to oxidative stress-induced dysfunction”, Antioxid. Redox Sign., in press (2017).
  2. CM Wong, AC Au, SY Tsang, CW Lau, X Yao, Z Cai, AC Chung, “Role of inducible nitric oxide synthase in endothelium-independent relaxation to raloxifene in rat aortas”, Brit. J. Pharmacol., 174(8), 718-733 (2017).
  3. S. Wang, X. M. Meng, Y. Y. Ng, F. Y. Ma, S. Zhou, Y. Zhang, C. Yang, X. R. Huang, J. Xiao, Y. Y. Wang, S. M. Ka, Y. J. Tang, A. C. Chung, K. F. To, DJ Nikolic-Paterson, H. Y. Lan, “TGF-β/Smad3 Signalling Regulates the Transition of Bone Marrowderived Macrophages into Myofibroblasts During Tissue Fibrosis’, Oncotarget, 7(8), 8809-8822 (2016).
  4. A. C. Chung, “MicroRNAs in Diabetic Kidney Disease”, Adv Exp Med Biol., 888, 253-69 (2015).
  5. Y. M. Yan, X. L. Wang, L. L. Zhou, F. J. Zhou, R. Li, Y. Tian, Z. L. Zuo, P. Fang, A. C. Chung, F. F. Hou, Y. X. Cheng, “Lingzhilactones from Ganoderma Lingzhi Ameliorate Adriamycin-induced Nephropathy in Mice”, J Ethnopharmacol., 176, 385-393 (2015).
  6. A. C. Chung, H. Y. Lan, “MicroRNAs in Renal Fibrosis”, Front Physiol., 6, 50-58 (2015).
  7. Q. Zhou, A. C. Chung, X. R. Huang, Y. Dong, X. Yu, H. Y. Lan, “Identification of Novel Long Noncoding RNAs Associated with TGF-β/Smad3-Mediated Renal Inflammation and Fibrosis by RNA Sequencing”, Am. J. Pathol., 184, 409-417 (2014).
  8. A. C. Chung, Y. Dong, W. Yang, X. Zhong, R. Li, H. Y. Lan, “Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs”, Molecular Therapy, 21, 388-398 (2013).
  9. Y. M. Yan, J. Ai, L. L. Zhou, A. C. Chung, R. Li, J. Nie, Y. X. Cheng, “Lingzhiols, Unprecedented Rotary Door-Shaped Meroterpenoids as Potent and Selective Inhibitors of p-Smad3 from Ganoderma lucidum”, Org. Lett., 15, 5488-5491 (2013).
  10. R. Li, A. C. Chung, Y. Dong, X. Zhong, H. Y. Lan, “miR-433 promotes Renal Fibrosis by targeting the TGF-b/Smad3- Azin1 Pathway”, Kidney International, 84, 1129-44, (2013). Commented by Kato M. TGF-β-induced signaling circuit loops mediated by microRNAs as new therapeutic targets for renal fibrosis? Kidney Int’l, 84, 1067-1069 (2013).
  11. A. C. Chung, H. Y. Lan, “Chemokines in renal injury”, J. Am. Soc. Nephrology, 22, 802-809 (2011).
  12. X. Zhong, A. C. Chung, H. Chen, X. Meng, H. Y. Lan, “Smad3-mediated upregulation of miR-21 promotes renal fibrosis”, Journal of American Society of Nephrology, 22, 1668-81, (2011).  Commented by Eddy AA. The TGF-beta route to renal fibrosis is not linear: The miR-21 Viaduct. Journal of American Society of Nephrology, 22, 1573-5 (2011).