Teaching Staff
 
KWONG, Daniel W. J. - Associate Professor, Associate Dean of Science
鄺維正博士

Educational Background
  • M.Sc., Yale, USA
  • Ph.D. (Chem. Eng.), Yale, USA
  • Ph.D. (Chem), Baylor, USA
  • Postdoctoral: U.S. A. Dept. of Energy Ames Research Laboratory, Iowa State University

Current Research Interests
  • bioinorganic photochemistry; development of novel porphyrinoids and their conjugates as tumor-imaging and photodynamic therapeutic agents; mechanistic studies of DNA photo-oxidative damage.

Contacts

Selected Publications
  1. K.-J. Wu, J.-M. Huang, H.-J. Zhong, Z.-Z. Dong, K. Vellaisamy, J.-J. Lu, X.-P. Chen, P. Chiu, D. W. J. Kwong, Q.-B. Han, D.-L. Ma, C.-H. Leung, “A Natural Product-like JAK2/STAT3 Inhibitor Induces Apoptosis of Malignant Melanoma Cells”, PLoS ONE, 12, e0177123 (2017).
  2. Y. Zhou, C.-F. Chan, D. W. J. Kwong, G.-L. Law, S. Cobb, W.-K. Wong, K.-L. Wong, “αvb3-Isoform Specific Erbium Complexes Highly Specific for Bladder Cancer Imaging and Photodynamic Therapy”, Chem. Comm., 53, 557-560 (2017).
  3. C. Yang, W. Wong, G.-D. Li, H.-J. Zhong, Z.-Z. Dong, C.-Y. Wong, D. W. J. Kwong, D.-L. Ma, C.-H. Leung, “Anticancer Osmium Complex Inhibitors of the HIF-1a and p300 Protein-Protein Interaction”, Sci. Rep., 7, 42860 (2017).
  4. J. Pan, L. Jiang, C.-F. Chan, T.-H. Tsoi, K.-K. Shiu, D. W. J. Kwong, W.-T. Wong, W.-K. Wong, K.-L. Wong, “Excitation Energy Transfer in Ruthenium (II)-Porphyrin Conjugates led to Enhanced Emission Quantum Yield and 1O2 Generation”, J. Luminescence, 184, 89-95 (2017).
  5. W. Wang, Z. Mao, M. Wang, L. J. Liu, D. W. J. Kwong, C. H. Leung, D. L. Ma, “A Long Lifetime Iridium(III) Complex Chemosensor for the Selective Switch-On Detection of Al3+ Ions”, Chem. Comm., 52, 3611-3614 (2016).
  6. D. Qi, Q. Wang, H. Li, T. Zhang, R. Lan, D. W. J. Kwong, W. K. Wong, K. L. Wong, S. Li, F. Lu, “SILAC-based Quantitative Proteomics Identified Lysosome as a Fast Response Target to PDT Agent Gd-N Induced Oxidative Stress in Human Ovarian Cancer IGROV1 Cells”, Mol. BioSyst., 11, 3059-3067 (2015).
  7. T. Zhang, R. Lan, L. Gong, B. Wu, Y. Wang, D. W. J. Kwong, W. K. Wong, K. L. Wong, D. Xing, “An Amphiphilic BODIPY-Porphyrin Conjugate: Intense Two-Photon Absorption and Rapid Cellular Uptake for Two-Photon-Induced Imaging and Photodynamic Therapy”, ChemBioChem, 16, 2357-2364 (2015).
  8. H. Li, R. Lan, C. F. Chan, L. Jiang, L. Dai, D. W. J. Kwong, M. H. W. Lam, K. L. Wong, “Real-time In-situ Monitoring via Europium Emission of the Photo-release of Antitumor Cisplatin from a Eu-Pt Complex”, Chem. Comm., 51, 14022-14025 (2015).
  9. L.-J. Liu, L. Lu, H.-J. Zhong, B. He, D. W. J. Kwong, D.-L. Ma, C.-H. Leung, “An Iridium(III) Complex Inhibits JMJD2 Activities and Acts as a Potential Epigenetic Modulator”, J. Med. Chem., 58, 6697-6703 (2015).
  10. C. H. Leung, L. J. Liu, L. Lu, B. He, D. W. J. Kwong, C. Y. Wong, D. L. Ma, “A Metal-Based Tumour Necrosis Factor-a Converting Enzyme Inhibitor”, Chem. Comm., 51, 3973-3976 (2015).
  11. L. Lu, D. S. H. Chan, D. W. J. Kwong, H. Z. He, C. H. Leung, D. L. Ma, “Detection of Nicking Endonuclease Activity using a G-quadruplex-selective Luminescent Switch-On Probe”, Chem. Sci., 5, 4561-4568 (2014).
  12. Z. Zhao, P. S. Chan, H. Li, K. L. Wong, R. N. S. Wong, N. K. Mak, J. Zhang, H. L. Tam, W. Y. Wong, D. W. J. Kwong, W. K. Wong, “Highly Selective Mitochondria-Targeting Amphiphilic Silicon(IV) Phthalocyanines with Axially Ligated Rhodamine B for Photodynamic Therapy”, Inorg. Chem., 51, 812-821 (2012).