Teaching Staff
LEE, Chi Sing (with appointment starts from 1 Sep 2018) - Associate Professor

Educational Background
  •     B.Sc., Indiana University of Pennsylvania
  •     Ph.D., University of Minnesota
  •     Postdoctoral: Medicinal Chemistry Division, Pharmacia Corporation
Professional Status
  • Honorary Associate Professor, Peking University Shenzhen Graduate School (2018–present)
  • Honorary Assistant Professor, University of Hong Kong (2002–2004, 2006–2008)
Current Research Interests
  • Natural Product Synthesis, Organic Methodology, Catalysis, Medicinal Chemistry, Chemical Biology and Molecular Imaging
  • Certificate for High-Level Professional in Shenzhen (2012–2017)
  • Asian Core Program Lectureship Award (2012)
  • Faculty Performance Award for Excellence in Research (2009)

Selected Publications (in recent five years)
  1. Zhu, L.; Ma, W.; Zhang, M.; Lee, M. M.-L.; Wong, W.-Y.; Chan, B. D.; Yang, Q.; Wong, W.-T.; Tai, W. C.-S.; Lee, C.-S. “Scalable Synthesis Enabling Multilevel Bio-Evaluations of Natural Products for Discovery of Lead Compounds” Nat. Commun. 2018, 9, 1283.
  2. Ye, W.; Huang, J.; Liang, Z.; Zhang, J.-X.; Lee, C.-S. “Responsive europium emission for paralytic shellfish saxitoxin detection in water” J. Lumin. 2018, 199, 28.
  3. Ma, W.; Liang, X.; Ye, W.; Wang, Y.; Min, L.; He, S.; Lee, C.-S. “Total Syntheses of Basiliolide A1, Basiliolide A2, Basiliolide C and their Structural Analogues” Eur. J. Org. Chem. 2018, 196.
  4. Yang, Q.; Ma, W.; Wang, G.; Bao, W.; Dong, X.; Laing, X.; L.; Zhu, L,; Lee, C.-S. “Tunable Cyclization Strategy for the Synthesis of Zizaene-, allo-Cedrane-, seco-Kaurane-, and seco-Atesane-Type Skeletons” Org. Lett. 2017, 19, 5324.
  5. Tsoi, T.-H.; Gu, Y.-J.; Lo, W.-S.; Wong, W.-T.; Wong, W.-T.; Ng, C.-F.; Lee, C.-S.; Wong, K.-L. “Study on the aggregation of DNA capped gold nanoparticles: a smart and flexible aptasensor for spermine sensing” ChemPlusChem 2017, 82,802.
  6. Du, G.; Wang, G.; Ma, W.; Yang, Q.; Bao, W.; Liang, X.; Zhu, L.; Lee, C.-S. “Syntheses of Diverse Natural Products via Dual-mode Lewis Acid Induced Cascade Cyclization Reactions” Synlett 2017, 28, 1394. (Invited Account)
  7. Liang, X.; Zhou, L.; Min, L.; Ye, W.; Bao, W.; Ma, W.; Yang, Q.; Qiao, F.; Zhang, X.; Lee, C.-S. “Diastereoselective Total Synthesis of (±)-Basiliolide B and (±)-epi-8-Basiliolide B” J. Org. Chem. 2017, 82, 3463.
  8. Liang, Z.; Tsoi, T.-H.; Chan, C.-F.; Dai, L.; Wu, Y.; Du, G.; Zhu, L.; Lee, C.-S.; Wong, W.-T. Law, G.-L.; Wong, K.-L. “A smart “off–on” gate for the in situ detection of hydrogen sulphide with Cu(II)-assisted europium emissionChem. Sci. 2016, 7, 2151.
  9. Du, G.; Bao, W.; Huang, J.; Huang, S.; Yue, H.; Yang, W.; Zhu, L.; Liang, Z.; Lee, C.-S. “Enantioselective Synthesis of the ABC-Tricyclic Core of Phomactin A by a γ-Hydroxylation Strategy” Org. Lett. 2015, 17, 2062.
  10. Liang, Z.; Chan, C.-F.; Liu, Y.; Wong, W.-T.; Lee, C.-S.; Law, G.-L.; Wong, K.-L. “The effects of the increasing number of the same chromophore on photosensitization of water-soluble cyclen-based europium complexes with potential for biological applicationsRSC Adv. 2015, 5, 13347.
  11. Yang, W.; Cao, J.; Zhang, M.; Lan, R.; Zhu, L.; Du, G.; He, S.; Lee, C.-S. “Systemic Study on the Biogenic Pathways of Yezo’otogirins: Total Synthesis and Antitumor Activities of (±)-Yezo’otogirin C and Its Structural AnaloguesJ. Org. Chem. 2015, 80, 836.
  12. Min, L.; Zhang, Y.; Liang, X.; Huang, J.; Bao, W.; Lee, C.-S. “A Biomimetic Synthesis of (±)-Basiliolide BAngew. Chem. Int. Ed. 2014, 53, 11294.
  13. He, S.; Yang, W.; Zhu, L.; Du, G.; Lee, C.-S. “Bioinspired Total Synthesis of (±)-Yezo’otogirin COrg. Lett. 2014, 16, 496. (Highlighted by E. M. Carreira in Synfacts)