Teaching Staff
 
CHUNG, Arthur, C. K. - Research Assistant Professor
鍾志剛

Educational Background:
  • B.Sc., The Chinese University of Hong Kong
  • M.Ph, The Chinese University of Hong Kong
  • Ph.D., University of Oklahoma, USA
  • Postdoctoral: Baylor College of Medicine, USA

Current Research Interests:

  • Persistent organic pollutants (POP), TGF-β signaling pathway, diabetes, renal diseases.
Contacts:  
Selected Publications:
  1. S. Wang, X. M. Meng, Y. Y. Ng, F. Y. Ma, S. Zhou, Y. Zhang, C. Yang, X. R. Huang, J. Xiao, Y. Y. Wang, S. M. Ka, Y. J. Tang, A. C. Chung, K. F. To, DJ Nikolic-Paterson, H. Y. Lan, “TGF-β/Smad3 Signalling Regulates the Transition of Bone Marrowderived Macrophages into Myofibroblasts During Tissue Fibrosis’, Oncotarget, 7(8), 8809-22 (2016).
  2. A. C. Chung, “MicroRNAs in Diabetic Kidney Disease’, Adv Exp Med Biol., 888, 253-69 (2015).
  3. Y. M. Yan, X. L. Wang, L. L. Zhou, F. J. Zhou, R. Li, Y. Tian, Z. L. Zuo, P. Fang, A. C. Chung, F. F. Hou, Y. X. Cheng, “Lingzhilactones from Ganoderma Lingzhi Ameliorate Adriamycin-induced Nephropathy in Mice”, J Ethnopharmacol., 176, 385-93 (2015).
  4. A. C. Chung, H. Y. Lan, “MicroRNAs in Renal Fibrosis”, Front Physiol., 6, 50-58 (2015).
  5. Q. Zhou, A. C. Chung, X. R. Huang, Y. Dong, X. Yu, H. Y. Lan, "Identification of Novel Long Noncoding RNAs Associated with TGF-β/Smad3-Mediated Renal Inflammation and Fibrosis by RNA Sequencing", American Journal of Pathology, 184, 409-17 (2014).
  6. A. C. Chung, Y. Dong, W. Yang, X. Zhong, R. Li, H. Y. Lan, "Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs", Molecular Therapy, 21, 388-98 (2013).
  7. Y. M. Yan, J. Ai, L. L. Zhou, A. C. Chung, R. Li, J. Nie, Y. X. Cheng, "Lingzhiols, Unprecedented Rotary Door-Shaped Meroterpenoids as Potent and Selective Inhibitors of p-Smad3 from Ganoderma lucidum", Organic Letters, 15, 5488-5491 (2013).
  8. R. Li, A. C. Chung, Y. Dong, X. Zhong, H. Y. Lan, "miR-433 promotes Renal Fibrosis by targeting the TGF-b/Smad3- Azin1 Pathway", Kidney International, 84, 1129-44, (2013). Commented by Kato M. TGF-β-induced signaling circuit loops mediated by microRNAs as new therapeutic targets for renal fibrosis? Kidney International 84, 1067–1069; (2013).
  9. A. C. Chung, H. Y. Lan, "Chemokines in renal injury", Journal of American Society of Nephrology, 22, 802-9, (2011).
  10. X. Zhong, A. C. Chung, H. Chen, X. Meng, H. Y. Lan, "Smad3-mediated upregulation of miR-21 promotes renal fibrosis", Journal of American Society of Nephrology, 22, 1668-81, (2011).  Commented by Eddy AA. The TGF-beta route to renal fibrosis is not linear: The miR-21 Viaduct. Journal of American Society of Nephrology, 22, 1573-5, (2011).
  11. A. C. Chung, H. Zhang, Y. Z. Kong, J. J. Tan, X. R. Huang, J. B. Kopp, H. Y. Lan, "Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling", Journal of American Society of Nephrology, 21, 249-60, (2010).
  12. C. Chung, X. R. Huang, X. M. Meng, H. Y. Lan, "miR-192 mediates TGF-β/Smad3- driven renal fibrosis", Journal of American Society of Nephrology, 21, 1317-25, (2010).