Teaching Staff
MA, Edmond D. L. - Associate Professor

Educational Background
  • B.Sc., The University of Hong Kong
  • Ph.D., The University of Hong Kong

Professional Appointments
  • Pre-proposals Evaluation Panel Member, French National Research Agency (ANR) 2016 Project Funding Selection Process
  • Invited Reviewer, National Science Center, Poland (Narodowe Centrum Nauki - NCN)
  • Invited Reviewer, the Czech Science Foundation (Grantová agentura České republiky, GA CR), Czech Republic 
  • Associate Editorial Board Member, American Journal of Neurodegenerative Disease (e-Century Publishing Corporation)
  • Senior Editorial Board Member, Journal of Nanoscience Letters (Publishing Division of Cognizure)
  • Editorial Board Member, Scientific Reports (Nature Publishing Group)
  • Editorial Board Member, Austin Alzheimer's and Parkinson's Disease (Austin Publishing Group)
  • Editorial Board Member, Austin Journal of Bioorganic & Organic Chemistry (Austin Publishing Group)
  • Editorial Board Member, Austin Journal of Biosensors & Bioelectronics (Austin Publishing Group)
  • Editorial Board Member, Global Journal of Pathology and Microbiology (Pharma Publisher)
  • Editorial Board Member, International Journal of Bioorganic Chemistry & Molecular Biology (SciDoc Publishers)
  • Editorial Board Member, International Research Journal of Pure and Applied Chemistry (SCIENCEDOMAIN international)
  • Editorial Board Member, Journal of Applied Chemical Science International (International Knowledge Press)
  • Editorial Board Member, Journal of Biopharmaceutics Sciences (Academic Research Publishers)
  • Editorial Board Member, Organic Chemistry: Current Research (OMICS International)
  • Editorial Board Member, Peertechz Journal of Medicinal Chemistry and Research (Peertechz)
  • Advisory Board Member, Journal of Materials Chemistry B (materials for biology and medicine) (Royal Society of Chemistry)
International Recognition
  • Listed as one of the top 1% of highly cited authors (Chinese scholars) in Royal Society of Chemistry journals in 2015
  • Listed in the Nature Index 2014 China by the Nature Publishing Group
  • Invited by the Croucher Foundation and The Royal Society as one of 70 outstanding early-career scientists to participate 2nd UK-Hong Kong Frontiers of Science Symposium
  • Invited by ChemComm as one of the best emerging scientists in the early stages of their independent career to contribute an article in Special issue - Emerging Investigator in 2014
  • Invited by ChemPlusChem as one of the rising star of the future to contribute an article in Special Issue - Early Career Series in 2014


  • President’s Award for Outstanding Young Researcher 2014 (Hong Kong Baptist University)
  • Nanoscience Research Leader Award 2015 (Publishing Division of Cognizure)
  • Single Publication Citation Award 2015 (Department of Chemistry, Hong Kong Baptist University)
  • Publication Excellence Award 2015 (Department of Chemistry, Hong Kong Baptist University)
  • National-level Technology Project Award for Advanced Individual 2015 (Shenzhen Virtual University Park, Science and Technology Innovation Commission of Shenzhen Municipality)
  • Provincial-level Technology Project Award for Advanced Individual 2015 (Shenzhen Virtual University Park, Science and Technology Innovation Commission of Shenzhen Municipality)

Current Research Interests
  • Luminescent probes
  • Computational structural biology
  • Structure-based drug design
  • Inorganic medicine


We are now looking for postdoctoral fellow and PhD student who can participate in our research projects on drug discovery and molecular probes. For further information, please contact Dr. Edmond Ma at edmondma@hkbu.edu.hk

Selected Publications
  1. L.-J. Liu, W. Wang, S.-Y. Huang, Y. Hong, G. Li , S. Lin, J. Tian, Z. Cai*, H.-M. D. Wang*, D.-L. Ma*, C.-H. Leung*. “Inhibition of the ras/raf interaction and repression of renal cancer xenografts in vivo by an enantiomeric iridium(III) metal-based compound” Chem. Sci., 2017, DOI:10.1039/C7SC00311K. (Invited as front cover)
  2. M. Wang, Z. Mao, T.-S. Kang, C.-Y. Wong, J.-L. Mergny*, C.-H. Leung* and D.-L. Ma*. “Conjugating a groove-binding motif to Ir(III) complex for the enhancement of G-quadruplex probe behavior” Chem. Sci., 2016, 7, 2516. 
  3. H.-J. Zhong, L. Lu, C. C. L. Wong, C. Peng, S.-C. Yan, D.-L. Ma*, Z. Cai*, H.-M. D. Wang*, C.-H. Leung*. “An iridium(III)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent” Chem. Sci., 2015, 6, 5400.
  4. S. Lin, W. Gao, Z. Tian, C. Yang, L. Lu, J.-L. Mergny*, C.-H. Leung*, D.-L. Ma*. “Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe” Chem. Sci., 20156, 4284.
  5. K.-H. Leung, H.-Z. He, B. He, H.-J. Zhong, S. Lin, Y.-T Wang, D.-L. Ma*, C.-H. Leung*. “Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe” Chem. Sci., 20156, 2166.
  6. D.-L. Ma*, D. S.-H. Chan, C.-H. Leung*. “Group 9 organometallic compounds for therapeutic and bioanalytical applications” Acc. Chem. Res., 2014, 47, 3614.
  7. L. Lu, D. S.-H. Chan, D.W.J. Kwong, H.-Z. He*, C.-H. Leung*, D.-L. Ma*. “Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe” Chem. Sci.2014, 5, 4561. (Invited as inside front cover)
  8. D.-L. Ma*, L.-J. Liu, K.-H. Leung, Y.-T. Chen, H.-J. Zhong, D. S.-H. Chan, H.-M. D. Wang*, C.-H. Leung*. “Antagonising STAT3 dimerization by a rhodium(III) complex” Angew. Chem. Int. Ed., 2014, 53, 9178. (Selected as a very important paper and invited as back cover; selected for News2WOWU publication by QS ranking institution)
  9. C.-H. Leung*, H.-J. Zhong, H. Yang, Z. Cheng, D. S.-H. Chan, V. P.-Y. Ma, R. Abagyan, C.-Y. Wong, D.-L. Ma*. “A metal-based inhibitor of tumor necrosis factor-α” Angew. Chem. Int. Ed., 2012, 51, 9010. (Invited as frontispiece)
  10. D.-L. Ma*, T. Xu, D. S.-H. Chan, B. Y.-W. Man, C.-H. Leung*. “A highly selective, label-free, homogenous luminescent switch-on probe for the detection of nanomolar transcription factor” Nucleic Acids Res., 2011, 39, e67.
  11. B. Y.-W. Man, H.-M. Chan, C.-H. Leung, D. S.-H. Chan, L.-P. Bai, Z.-H. Jiang, H.-W. Li*, D.-L. Ma*. “Group 9 metal-based inhibitors of β-amyloid (1–40) fibrillation as potential therapeutic agents for Alzheimer’s disease” Chem. Sci., 2011, 2, 917. (Highlighted by Noteworthy Chemistry, May 30, 2011)
  12. D. S.-H. Chan, H.-M. Lee, F. Yang, C.-M. Che, C. C. L. Wong, R. Abagyan, C.-H. Leung*, D.-L. Ma*. “Structure-based discovery of natural product-like TNF-α inhibitors” Angew. Chem. Int. Ed., 2010, 49, 2860. (Invited as frontispiece (April issue 2010); chosen as a “Hot Paper” by the Editors for the importance in a rapidly evolving field of high current interest; highlighted by Nature SciBX, 3, DOI:10.1038/scibx.2010.398)