Teaching Staff
MA, Edmond D. L. - Associate Professor

Educational Background
  • B.Sc., The University of Hong Kong
  • Ph.D., The University of Hong Kong


We are now looking for postdoctoral fellow and PhD student who can participate in our research projects on drug discovery and molecular probes. For further information, please contact Dr. Edmond Ma at edmondma@hkbu.edu.hk

Selected Publications:
  1. G.-J. Yang, W. Wang, W.-F. S. Mok, C. Wu, Y.-K. B. Law, X.-M. Miao, K.-J. Wu, H.-J. Zhong, C.-Y. Wong, K.-W. V. Wong,* D.-L. Ma,* C.-H. Leung,* “Selective Inhibition of Lysine-specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-negative Breast Cancer Therapy”, Angew. Chem. Int. Ed., in press (2018).
  2. K. Vellaisamy, G. Li, C.-N. Ko, H.-J. Zhong, S. Fatima, H.-Y. Kwan, C.-Y. Wong, W.-J. Kwong,* W. Tan,* C.-H. Leung,* D.-L. Ma,* "Cell Imaging of Dopamine Receptor Using Agonist Labeling Iridium(III) Complex", Chem. Sci., 9, 1119 (2018).
  3. L.-J. Liu, W. Wang, S.-Y. Huang, Y. Hong, G. Li, S. Lin, J. Tian, Z. Cai,* H.-M. D. Wang,* D.-L. Ma,* C.-H. Leung,* “Inhibition of the Ras/Raf Interaction and Repression of Renal Cancer Xenografts In Vivo by an Enantiomeric Iridium(III) Metal-based Compound”, Chem. Sci., 8, 4756 (2017). (Invited as front cover)
  4. M. Wang, Z. Mao, T.-S. Kang, C.-Y. Wong, J.-L. Mergny,* C.-H. Leung,* D.-L. Ma,* “Conjugating A Groove-binding Motif to Ir(III) Complex for the Enhancement of G-quadruplex Probe Behavior”, Chem. Sci., 7, 2516 (2016).
  5. H.-J. Zhong, L. Lu, C. C.-L. Wong, C. Peng, S.-C. Yan, D.-L. Ma,* Z. Cai,* H.-M. D. Wang,* C.-H. Leung,* “An Iridium(III)-based Irreversible Protein-protein Interaction Inhibitor of BRD4 as A Potent Anticancer Agent”, Chem. Sci., 6, 5400 (2015).
  6. S. Lin, W. Gao, Z. Tian, C. Yang, L. Lu, J.-L. Mergny,* C.-H. Leung,* D.-L. Ma,* “Luminescence Switch-on Detection of Protein Tyrosine Kinase-7 Using A G-quadruplex-selective Probe”, Chem. Sci.6, 4284 (2015).
  7. D.-L. Ma,* L.-J. Liu, K.-H. Leung, Y.-T. Chen, H.-J. Zhong, D. S.-H. Chan, H.-M. D. Wang,* C.-H. Leung,* “Antagonising STAT3 Dimerization by a Rhodium(III) Complex”, Angew. Chem. Int. Ed., 53, 9178 (2014). (Selected as a very important paper and invited as back cover)
  8. C.-H. Leung,* H.-J. Zhong, H. Yang, Z. Cheng, D. S.-H. Chan, V. P.-Y. Ma, R. Abagyan, C.-Y. Wong, D.-L. Ma,* “A Metal-based Inhibitor of Tumor Necrosis Factor-α”, Angew. Chem. Int. Ed., 51, 9010 (2012). (Invited as frontispiece)
  9. D.-L. Ma,* T. Xu, D. S.-H. Chan, B. Y.-W. Man, C.-H. Leung,* “A Highly Selective, Label-free, Homogenous Luminescent Switch-on Probe for the Detection of Nanomolar Transcription Factor”, Nucleic Acids Res., 39, e67 (2011).
  10. D. S.-H. Chan, H.-M. Lee, F. Yang, C.-M. Che, C. C.-L. Wong, R. Abagyan, C.-H. Leung,* D.-L. Ma,* “Structure-Based Discovery of Natural Product-Like TNF-α Inhibitors”, Angew. Chem. Int. Ed., 49, 2860 (2010). (Invited as frontispiece, chosen as a “Hot Paper” by the Editors for the importance in a rapidly evolving field of high current interest and highlighted by Nature SciBX)
  11. D.-L. Ma, C.-M. Che,* S.-C. Yan. “Platinum(II) Complexes with Dipyridophenazine Ligands as Human Telomerase Inhibitors and Luminescent Probes for G-Quadruplex DNA”, J. Am. Chem. Soc.131, 1835 (2009). (Highlighted by C & E News)
  12. D.-L. Ma, W.-L. Wong, W.-H. Chung, F.-Y. Chan, P.-K. So, T.-S. Lai, Z.-Y. Zhou, Y.-C. Leung, K.-Y. Wong,* “A Highly Selective Luminescence Switch-on Sensor for Histidine/Histidine-rich proteins and Its Application in Protein Staining”, Angew. Chem. Int. Ed., 47, 3735 (2008). (Highlighted by Nature Publishing Group (NPG) Asia Materials)