Teaching Staff
CHAN, Wing Hong - Emeritus Professor

Educational Background
  • B.Sc. (Hons.), The Chinese University of Hong Kong
  • Ph.D., Alberta, Canada
  • Postdoctoral: UCLA, USA

Current Research Interests
  • organic synthesis and analysis;
  • chemical sensors;
  • supramolecular chemistry;
  • chemical education.



Selected Publications
  1. Y. Li, Y. Zhao, W. H. Chan, Y. Wang, Q. You, C. Liu, J. Zheng, J. Li, S. Yang, R. H. Yang, “Selective Tracking of Lysosomal Cu2+ Ions Using Simultaneous Target- and Location Activated Fluorescent Nanoprobe”, Anal. Chem., 87, 584-591 (2015).
  2. Q. You, Y. M. Lee, W. H. Chan, N. K. Mak, A. W. M. Lee, S. C. K. Hau, T. C. W. Mak, “A colorimetric and ratiometric fluorescent pH probe based on ring opening/closing approach and its applications in monitoring cellular pH change”, RSC Advances, 5, 4099-4102 (2015).
  3. Q. You, A. W. M. Lee, W. H. Chan, X. Zhu, K. C. F. Leung, “A coumarin-based fluorescent probe for recognition of Cu2+ and fast detection of histidine in hard-to-transfect cells by a sensing ensemble approach”, Chem. Commun., 50, 6207-6210 (2014).
  4. J. Li, T. Yang, W. H. Chan, M. F. Choi, “Synthesis of High-Quality N-Acetyl-L-Cysteine-capped CdTe Quantum Dots by Hydrothermal Route and the Characterization through MALDI-TOF Mass Spectrometry’, J. Phys. Chem. C, 117, 19175-19181 (2013).
  5. Y.-P. Chan, L. Fan, Q. You, W. H. Chan, A. W. M. Lee, S. Shuang, “Ratiometric pH responsive fluorescent probes operative on ESIPT”, Tetrahedron, 69, 5874-5879 (2013).
  6. Q. You, P. -S. Chan, W. H. Chan, S. C. K. Hau, A. W. M. Lee, N. K. Mak, T. C. W. Mak, R. N. S. Wong, “A quinolinyl antipyrine based fluorescence sensor for Zn2+ and its application in bioimaging”, RSC Advances, 2, 11078-11083 (2012).
  7. H.-M. Chan, L. Xiao, K.-M. Yeung, S.-L. Ho, D. Xiao, W. H. Chan, H. W. Li, “Effect of surface-functionalized nanoparticles on the elongation phase of beta-amyloid (1-40) fibrillogenesis”, Biomaterials, 33, 4443-4450 (2012).
  8. J.-F. Zhu, A. W. M. Lee, W. H. Chan, “Both Visual and Rationmetric Fluorescent Sensor for Zn2+ Based Spirobenzopyran Platform”, Tetrahedron Lett., 53, 2001-2004 (2012).
  9. X. B. Zhou, W. H. Chan, A. W. M. Lee, P. S. Chan, R. N. S. Wong, N. K. Mak, “Ratiometric fluorescent Zn2+ chemosensor constructed by appending a pair of carboxamidoquinoline on 1,2-diaminocyclohexane scaffold”, Tetrahedron, 67, 3412-3419 (2011).
  10. B.-J. Pei, W. H. Chan, A. W. M. Lee, “Anthracene Capped Isobenzofuran: A Synthon for the preparations of Iptycenes and Iptycene Quinones”, Org. Lett., 13, 1774-1777 (2011).
  11. W.H. Chan, D. Zhao, Z. He N.K. Mak, R.N.S. Wong, A.W.M. Lee, P. Chan, “NAC-Capped Quantum Dot as Nuclear Staining Agent for Living Cells via an In Vivo Steering Strategy”, J. Phys. Chem. C, 114, 6216-6221 (2010).
  12. N. Shao, J. Jin, H. Wang, J. Zeng, R.H. Yang, W.H. Chan, “Design of Bis-spiropyran Ligands as Dipolar Molecule Receptors and Application to in vivo Glutathione Fluorescent Probes”, J. Am. Chem. Soc., 132, 725-736 (201